Acitop – Fever Blister Cream (2g)


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SKU: 873551001 Category:


Composition: Each gram of cream contains 50 mg of acyclovir. (5.0 % w/w acyclovir). Preservative: Chlorocresol 0,12% m/m. Pharmacological classification: A 20.2.8. Antiviral agent. Pharmacological action: Acyclovir is an acyclic guanine nucleoside analogue that lacks the 3′-hydroxyl on the side chain. It is active against herpes simplex virus type 1 and 2. Acyclovir is phosphorylated intracellularly by viral thymidine kinase to the active triphosphate that inhibits viral DNA synthesis and replication by inhibiting the viral DNA polymerase enzymes. The active triphosphate is also incorporated into the herpes virus DNA. Normal cellular processes are not affected. Indications: Acitop is indicated for the symptomatic treatment of herpes simplex infections of the lips. Both the initial and recurrent infections can be successfully treated. Contra-indications: Hypersensitivity to acyclovir, propylglycol and chlorocresol. Identification: A white to off- white smooth cream.